CIIMAR’s Neptune Seminar with Diana Sousa | Boca da Baleia
Cyanobacteria are prolific producers of structurally diverse secondary metabolites. Recent studies demonstrated that restricting natural products (NPs) mining to cultivable strains results in the loss of a huge portion of the Phylum biosynthetic potential. Numerous biosynthetic gene clusters (BGCs) present in the genomes of uncultured cyanobacteria lack an associated metabolite – cryptic/orphan BGCs. The work presented on this seminar focuses on the application of low- and high-throughput BGC capturing techniques for the deorphanization of BGCs encoded on the genomes of biofilm forming cyanobacteria collected during CIIMAR sampling campaigns.
Diana holds a BSc degree in Biochemistry (FCUP/ICBAS-UP), and a MSc degree in Applications in Biotechnology and Synthetic Biology (FCUP). She’s currently on the second year of her PhD in Biomedical Sciences (ICBAS-UP). Her project focuses on the discovery of novel secondary metabolites produced by biofilm forming cyanobacteria. Her main research interests include meta-omics, synthetic biology, natural products biosynthesis and unnatural natural products.
In case of any questions, please contact CIIMAR’s Seminar team, Marta Monteiro, Miguel Semedo, & Paulo Oliveira, at seminars@ciimar.up.pt
External members of CIIMAR should send an email to slopes@ciimar.up.pt, requesting authorization to enter the Porto Cruise Terminal area
CIIMAR members can also access last seminars recordings through the LINK.
