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National R&D

PROZYME

Principal Investigator
Researcher

Cláudia R. Serra holds a PhD in Biology (ITQB-NOVA) and is currently Assistant Researcher at CIIMAR and Invited Assistant Professor at the Faculty of Sciences of the University of Porto, FCUP. She is a molecular microbiologist currently dedicated to the characterization of gastrointestinal microbial communities of economically important fish species. Her research interests include the application of microbial genetics and molecular biology tools in the functional analysis of bacterial genomes, identifying and characterizing genes of gastrointestinal isolates with biotechnological potential, and the development of microbial-based strategies to fight aquaculture problems, including novel probiotics and vaccines. Claudia has more than 20 years of practical lab experience in academic settings with strong connections to pharma and animal-feed industries, counting with 3 patents, 1 licensing-agreement, and several prizes in technology transfer activities. 

RESEARCH GROUPS:

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Aquaculture sustainability requires replacement of fish meal (FM) by plant feedstuffs (PF) in aquafeeds to reduce diet costs and environmental impacts associated with FM use.

PF nutritive value is limited by the presence of non-starch polysaccharides (NSP), which cannot be hydrolysed by fish digestive enzymes, becoming a source of organic pollutants and negatively impacting fish performance and gut health.
ProZyme refers to an innovative solution using Probiotic bacteria (PRO) capable of producing NSP hydrolysing enzymes allowing the host to obtain energy from indigestible nutrients, reduce fecal matter production and NSP harmful effects in fish gut. By acting as prophylactic agents, decreasing disease incidence, PRoZyme will also reduce antibiotic use in aquaculture and associated environmental impacts and risks to human health, contributing to the improvement of fish health and the sustainability of aquaculture.
This project aims at the protection of the invention ProZyme through national and international patent. The international patent application will represent a competitive advantage in the search for new economic partners to support the developments needed to take ProZyme to market and to ensure an effective commercialization. The internationalization of the patent will support the dissemination of technology, increasing the possibilities to transfer the technology, ideally to a national company, stimulating national competitiveness.

 

PROJECT SHEET

Leader Institution
CIIMAR-UP
Program
Portugal 2020
Funding
Other projects